Research Paper: Fatigue in patients with acquired brain damage- by Dr.Afshan Hashmi

0:00 This program is designed to provide general information with regards to the subject matters covered. This information is given with the understanding that neither the hosts, guests, sponsors or station are engaged in rendering any specific and personal medical, financial, legal, counseling, professional service, or any advice. You should seek the services of competent professionals before applying or trying any suggested ideas. Books, pdproducts, science, fashion and glam talk from Bollywood to Hollywood. It's Meet and greet with doctor Ashan Hashmi right here on KURHD Radio and Talk for TV. And here's your host, international speaker, educator, award winning entrepreneur and best selling author, doctor Afshan Hashmi.

0:55 Hello everyone, this is your loving host and best selling authors, radio and TV personality doctor Rafshan Hashmi live from a studio in Rockville, Maryland, and today, folks, you know, I want to wish everyone a happy and a blessed Easter. And I love to celebrate Easter because you know, Easter is a Christian holiday. But you know I have studied, you know, from a Christian machinery school in India, and so we used to celebrate Easter and hunt for eggs and all. So I want to wish everyone happy Easter. And I went to the mall and got this photograph. You know, mate, I want to do these kind of fun things, you know, and I wanted to share that.

1:41 And then I made these photographs you know, and this one see and this one and this one see. So how did you like them? I would love, you know, people you know, comment on that. And before we dive into the show, these are my two books. The first one is the Modern Local Mentality, New Strategies to Succeed in India and the global marketplace, and the second one is The Outbreak of a Monstrous Infection. So these books, you know, both were mson best sellers, and this one was Amazon bestseller in USA and India and hot number one new release in USA, and the Outbreak of a Monster's Infection was Amazon bestseller in USA. And also, you know, I want a movie or a documentary to be made of the Modern Local Mentality and for Outbreak of a Monsters Infection, I want a movie or a web series to be made. And tail Flix has given me a very good evaluation of this. So those all those tail flicks, you know, all those producers, please go and look at it.

2:51 On my website www dot shanhash mei dot com where you will see tail Flix evaluation and also please go to please go and give me a sponsorship also and please go and make this movie or documentary and web series or TV serial and please contact me all those documentary web series and Hollywood Bollywood and if you net Netflix and Amazon, if you want, you know, to do that, to do the interview, you know, please to please you know, if you want to interview me for that, please contact me at augh Shan at yarra shan Hashmi at dot com.

3:36 And I I am looking for guests on my show, so please go. If you want to come on my show, please contact me at augh Shan at arrashanhash me dot com. And I would love love to host many of you. And there is a price of that and I gave a very nominal price and I have If you go to my website www dot shanhash me dot com, you will that there I have put up a life story kind of a thing, you know, So in five thousand dollars, you know, I will give you five settings you know, and I will do like a. Like a life story. I will interview you for one hour and then you know, I will give you one uh one edit of of uh this edition of the whole thing, and then I will give you the file as well as.

4:31 I will load the file. Having said that, folks, you know now I will be talking about this paper, you know. And and but before us dive in, I want to read a little bit from the study around. So the sura, which is open, is a column yes, and it says it is said that the Korash were trying to attack the profit through the use of the evil eye, but that this verse was revealed as a means of protection. According to one report, there was a man among the Arabs who used to abstain from food for two or three days and then raise part of his tenth as the cattle passed by, and say there are no grazing camels or cheap today better than these, And the cattle would not proceed far before some of them would fall dead. That disbelievers ask this man to give the evil to the messenger of God.

5:25 But God protected his profit and revealed this verse. Although some attribute the evil lie, which afflicts people with misfortune through envy and jealousy, to legend to profit is reported to as seek refuge in God, for the evil eye is real in this way, and he enjoyed his companions. One of you see something of his brother or himself or his wealth that he admiresed them. Glorify God, for the evil is real. And I have another proposal, So this is from the Holy Koran, the study Ran, and I have another proposal for my I'm looking for a sponsorship for my show, and for five thousand dollars I.

6:07 Will give you. You know, I will give you two let me say all together eight eight sittings of thirty minutes each and in that thirty minute, five minutes will be your ad and the rest twenty five minutes I will give you in eight podcasts, and I will distribute it to all the more than one hundred outlets. And you can go to my website and radio website s ttp slash slash www dot Doctor of Shanhashm's radio dot com. And you can see that website on www dot shanhash Me dot com.

6:48 So if you or you can google me doctor of shan Hashmi's Radio Show. So this is what I wanted to tell you, folks. And now I will go on a break and will be back. So allow viewers around the group. This is Doctor of Cham Hatchman, the Live. For her radio show at K four SHB and Talk for TV Show, And I just wanted to request you that please give me a sponsorship if you want to. Want this show to continue. Having set that fence, I will see you in another episode of K four st Radio plus Talk for TV Show. And if you give me.

7:34 A sponsorship, I will give you a very. Reasonable price and they'll also you will get a lot of promotion as this show is syndicated your right to move them through. Last cheers and bye bye. Would you love exposure for your business, product or service to over three hundred million potential listeners? Send an email to invo at talk form com and now let's hear from some of our sponsors. Chapter two, How Jugar leads to multi sector sex stories in India, including definitions of the Jugar management, principal business model of the book, the Modern Mobile mentality, News strategies to Succeed in India, and the global marketplace inspiration Thrue Jugar is an inspiration on how to create products using technology that meet the price value equation. According to a Harvard Business Review article featuring expert prellad than Marshalker. Most innovation programs are built on the assumptions of affluence and abundance.

8:52 We see the rich and the young in both the developed and the developing countries demanding environmental friendly products and services. They also believe. That affordability and sustainability are crucial to driving successful business Today. New technologies and radical business models are important not only to penetrate mass markets in India but in the entire world. By reconfigure during all areas of the business structure, they will puld.

9:35 Hey, monstrous infection is spreading worldwide. OMG. Is this a simple infection or a deliberate attempt to ruin the human population? Or maybe it's bio terrorism. What is this global infection and who is spreading it? Help us find out. Go to Amazon and search for the outbreak of a monstrous infection. The human race nature helped make this go viral. Go to Amazon dot com and read the Outbreak of a monstrous infection to find out what happens next. Go now the world is depending on you, and now doctor ash on Hashme's radio show.

10:31 So now it is. The paper is in Neurologia and Journal, and the paper is called fatigue in patients with a quiet brain damage by age Hores Belonde. And here it is, And I wanted to talk about illegal droning and illegal espionage. Me and my parents and my family has been a victim of illegal droning and illegal espionage for more than twenty years. And because of that, you know, from twenty eleven to twenty fifteen, there were many deaths in the family, my father, my mother, my younger autistic brother. And now in twenty sixteen January, my ex fiancee was dead. And then, you know, because of illegal roning and illegal espionage, and also because of illegal espionage and illegal droning, my husband was killed, you know, last year and he was completely fine, and he got dementia and parkinson and that is a terminal disease.

11:47 So now, folks, you know, I have to tell you that what should I do regarding it? So I did a literature search and I found out this paper. Because I have also become quite slow. You know, there's sometimes there is so much of illegal droning and illegal espionage in my house. My house is a mess, you know, things are breaking down, and you know what I came because of all this and I'm waiting for Although I have insurance, I'm waiting for them for past one year. They haven't come to give me the cleanup of the house and everything. So what I Am going to do is go and do this is that I will read this that how I feel fatigue. After this show, I will go and do some exercise, you know. And that helped me yesterday I went there. That helped me. So I said, however much exercise I can do, I should do that. And it says fatigue is a complex, multi dimensional syndrome that is prevalent in patients. And yes, I want to do a disclaimer. I'm a PhD doctor with PhD in biochemistry, with PhD in biochemistry and see chemistry clinical chemistry certification from American Society of Clinical Pathology and this one is Regulatory Affairs certified. So and I have

13:20 done a lot of clinical research. Even my PHDAR was on blood cells, you know how the how hemoglobin different kinds of hemoglobin was in my m film and then effects of fenyl hydrazine on red blood cell membrane. And you can do a pub spem met search on me. And I was able to write a paper. So now folks you know, this is a very important thing that the people should So if you are having fatigue, don't just sit go and talk to your medical professional. I go there every month, you know, and I get myself checked. But you never know what can irrupt because of this illegal droning and illegal espionage. And see, because of that, I have so many of white spots here. See this, this is not a very good sign, you know. So I have to get a full cleanup, you know, of my body, you know, And yesterday I dispensed. I don't know how much impurity, and I don't know how it came into my body. So, you know, fatigue is a complex, multi dimensional syndrome that is prevalent in patients with a quiet brain damage and has a negative impact on the neuro rehabilitation process. I feel that, you know, my husband was not given the right treatment, you know, and he was so much illegally droned and illegal espionage that you know,

14:51 it all happened to him and eventually he died. And we see very young people. I see so many sick children around in this county. This is one of the most expensive counties after Hollywood, you know, and it is near Washington, DC. I live in suburbs of Washington, DC metro area, and it is very expensive out here to live here. So you know, if we do, if we. Become slow, and if we cannot you know, earn money or anything because of this disease. I don't have any children.

15:31 My husband has died, so I am in a very very difficult situation. What tomorrow If I die in the house due to illegal droning and illegal espionage, there is nobody to look after me. So just think about all these consequences. And people who do illegal droning and illegal espionage are terrorists. That's what I feel about them. And it presents from early stages after injury and may persist over time regardless of weather. Squally have resolved. Fatigue is conditioned by neural circuits and is defined as an abnormal perception of over exhaustion.

16:16 So you know, here I have like here, I have pain. You know sometimes I have pain here and it can lead to tumor, you know. So, and I am very young. So illegal droning and illegal lespinach inhibits that neuro rehabilitation process. So you know, if you get illegally droned and you get clinically cleaned, you know, by your doctor and all. And then again they don't do droning, you know, so that high and low can make you very very sick and also very very very susceptible to diseases. And please go and consult your physician. I am not a physician.

17:02 I am just a researcher. And now I have left research and I do my radio show. But whatever knowledge I have acquired, I go to permud and do search and the paper of today's interest. I have what what population, American population or global population needs to know. I go and search for those kind of papers, you know. Having said that, folks, now I will go on a break and will be back soon. Agreement around the I am with you strange and talk for few friends. I am like Maryland in a country club.

17:46 And I just limited to say that please her search which. Go on. For money to produce these coal Having said gipons. He. Would you love exposure for your business, product or service to over three hundred million potential listeners. Send an email to info at talkformedia dot com. And now let's hear from some of our sponsors.

18:34 A monstrous infection is spreading worldwide. Oh my god, is this a simple infection or a deliberate attempt to ruin the human population, or maybe it's bioterrorism. What is this global infection and who is spreading it? Help us find out. Go to Amazon and search for the Outbreak of a Monstrous Infection. The human race needs your help to make this go viral. Go to Amazon dot com and read the Outbreak of a Monstrous Infection to find out what happens next. Go now, the world is depending on you.

19:21 The Outbreak of a Monstrous Infection Chapter one, nineteen sixty four to twenty eighteen. And this is the sample track and it is read by doctor Rafshan Nahid Hashmi in a sprawling banglaw In Potomac, Maryland, USA, live doctor Honey Singh, a both certified internal medicine and family practice physician. Along with his beautiful wife, Baby Singh. Baby Singh was a fashionista and was funding women's causes through her Honeybay Foundation. She had a lady's book club by the name of Baby's Blam and Glitzy Club which had many glam and glidsey ladies who were professionals living in Washington, d C. Potomac, Maryland, Virginia, and even Beverly Hills, California, as well as alde from all of America, meeting at her place on the last Wednesday of every month, discussing various aspects of charities they wanted her and doctor Honey to fund. In this club, there was a wide spectrum of career women. There were doctors, lawyers, actresses, business owners, and models to name a few. In these book club meetings, members would come prepared after reading a book of a famous woman author, and that author was even invited from any part of the world to give her presentation, followed by a Q and A in this prestigious and elite gathering.

20:53 And now thanks to doctor Offshan Hashmi's radio. Shows, introduction acquired brain energy ABI is recognized by the World Health Organization as the leading cause of disability worldwide. Stroke is the most frequent type of ABI, with an incidence of one hundred and fifty to two hundred cases per one hundred thousand persons years. In Spain, this rate is similar to that of traumatic brain injury TBI, with two hundred cases per one hundred thousand person years. Other less frequent types of ABI are brain tumor surgery and so in fellopathy, and encephalitis. Fatigue is common in patients with ABI and has a negative impact on neuro rehabilitation, hindering their involvement in treatment and recovery in the long term.

21:51 This review aims to summarize the evaluable evidence on some relevant aspects of fatigue. In ABI definition, fatigue is a sensation of exhaust exhaustion, lack of energy, and aversion to effort that may develop during physical or mental activity and that usually does not decrease with rest. The difference between fatigue and tireedness is that while the latter is proportional to the effort exerted, the formal is associated with an exaggerated disapproptionate perception of effort. Fatigue is a complex, multi dimensional concept with psychological, motivational, situational, and physical dimensions. As in other brain disorders, following a BI, fatigue is a consequence of an abnormal perception of over exertion and the consequent disruption of descending motor pathways. Several classifications of fatigue have been proposed based on this concept, So some researchers and again, I'm having pain here, so now I will go on a brain can will be back soon. Hello, everyone.

23:03 This is Doctor of Shan Hashni live from a barn country club in Virginia, and I just wanted to say that my K four SHD radio and top for TV show called Me Andy with Doctor of Shankshni is syndicated worldwide and has more than three hundred million listeners. And if you want these shows to continue, please gave a sponsorship. And I request to please give a sponsorship because these shows require a lot of energy and money to produce. So I would request every month to give me sponsorship and your product quid be promoted in a very reasonable price.

23:47 And you can contact me Atafshan at Trufshanhashmi dot com. Peers and bye bye. Would you love exposure for your business, product or service to over three hundred million potential listeners, Send an email to invo at talkform media dot com. And now let's hear from some of our sponsors. Chapter two, How Jugar leads to multi sector sex stories in India, including definitions of the Jugar management, principal business model of the book, the modern mobile mentality, news strategies to succeed in India and the global marketplace inspiration through Jugar is an inspiration on how to create products using technology that meet the price value equation. According to a Harvard Business Review article featuring expert prellad Than Marshalker, most innovation programs are built on the assumptions of affluence and abundance.

24:58 We see the rich and the young in both the developed and the developing countries demanding environmental friendly products and services. They also believe. That affordability and sustainability are crucial to driving successful business Today. New technologies and radical business models are important not only to penetrate mass markets in India but in the entire world. By reconfigure during all areas of the business structure, they will puld.

25:41 Hey, monsters, infection is spreading worldwide. OMG. Is this a simple infection or deliberate chempt to ruin the human population? Or maybe it's biothermrorism? What is this global infection and who is spreading it? Help us find out? Got Amazon and search for the outbreak of a monstrous infection. The human race needs your help to make this go viral. Go to Amazon dot com and read the Outbreak of a Monstrous Infection to find out what happens next. Go now. The world is depending on you and now back to doctor ash on Hashme's radio show.

26:36 In the So now this is here and the time is only you know, it's six twenty seven and fifteen minutes are left, so I cannot read the whole paper. If you are interested, please go and look for the papers. And then it says epidemiology. In the field of neurology, fatigue is high prevalent in patients with such conditions as multiple is chlorosis eighty percent to ninety percent. In the context of acquired neurological injuries, the prevalence of fatigue in patients with his spinal cord injury ranges from fifty to fifty seven percent from very early stages persisting over the course of the disease. So this is what it is and fatigue in patients with acquired brain injury. Several modi modifiable and non medifiable factors explain not only the appearance of fatigue, but also progression or worsening over time pathop physiology.

27:40 The path of physiology of fatigue in ABI is unknown, however, as this is a distinct phenomena occurring in patients with a wide range of neurological disease. Deeper understanding of his path of physiological basis in conditions unrelated to ABI, meys shed light on the mechanism and potential for fatigue link to ABI. Several trigger factors have been proposed at the neuronal and neurotransmission level, alterations in cortical excitability, at the neuroanatomical level localization of specific legions, and at the genetic and epigenetic level, alterations in metabolic and inflammatory mechanisms.

28:26 Post stroke fatigue. Stroke is the leading cause of death and disability in many countries. Due to the lack of universal definition of fatigue, it is not possible to establish the exact prevalence and incidents of this complication. For fatigue following traumatic brain injury TBI is very frequent in neuro rehabilitation units, which explain why it is the second most studied disease and is associated with high prevalence rates of post TBI fatigue. Although most cases of TB are mild, with non specific symptoms resolving within three to six months, some patients present silent residual symptoms known as post concursive symptoms, for example fatigue, which have a negative impact on the patient's social reintegration A study of professional required players reported a prevalence rate of fourteen point one percent for fatigue. This was the most symptom, followed by neck pain eleven point five percent.

29:29 Fatigue is the somatic symptom most frequently reported by patients with TBI and the most severe secondary symptoms. Review studies in pediratic population concluded that the prevalence of post ABI fatigue in this population ranges from sixty one point seven percent to sixty four point two percent. In America. You know, if you are brained, you are dead. So you know this is a very very You know, the terrorists are using a throwing drow owns illegally in people's houses, and they are you know, doing these kinds of things by illegal droning and illegal espionage. So you know, it is very easy to kill someone. But just think about how their family feels. And if a person has killed someone, you know, I think that person is a terrorist and.

30:24 Is a beast. So now, rehabilitation, let me see the time. Yes, rehabilitation therapy hospital neuro rehabilitation units. But ensure regular access to fresh air, a homelike environment allowing quite rest and leisure areas. These are vulnerable population. And since my husband has died, you know, many people you know bully me and all you know, and they think as if I am very rich or anything. Well, I am just a common girl, you know, door girl who struggles with the bills. You know, every time, you know, when the month comes, they struggle with the bills. I'm short of money all the time.

31:10 So you know, I am not rich or anything. And if you bully me, of course I will report it to the authorities. And it is a very easy way to kill someone by giving them pressure over here, here or anywhere, and that is brain injury. So those kind of injuries, you know, lead to people's death. And my husband was completely fine till he had induced dementia and induced partinism. And how he has deteriorated in a few months, you know, it is very very very very very strange, you know, and he didn't get the right treatment. So now this is the rehabilitation therapy they have discussed. It's a review, so they have discussed that, and let's see what are the conclusions. Fatigue is highly and here is the conclusion. Fatigue is a highly prevalent syndrome in patients with such knowlogical diseases as multiple sclorossis. Fatigue is also highly prevalent, through less well understood after the ABI. Fatigue seems to be more frequent after STOKE and TBI, although it is being increasingly detected in patients with such other conditions as neoplastic brain tumors, in cephalopathy and incephalitis. Fatigue is defined as a feeling of exhauction, lack of energy, and aversion to effort that may develop during physical or mental activity and that usually does not decrease with rest.

32:42 It may be interpreted from a central cognitive and mental aspects or a peripheral perspect motor and physical aspects, as well as from a path of physological perspective central and peripheral NETWAUS system is structures. It is caused by alterations in neural activity secondary to injury, as well as bi genetic and epigenetic changes associated with metabolic and inflammatory mechanisms. Fatigue persist over time after complete or parture recovery from other limitations. It has a negative impact on quality of life, with patients presenting poorer long term performance than individuals without the syndrome. At present, fatigue is mainly studied with clinical assessment scales. There is currently no consensus on the most appropriate pharmacological and non pharmacological treatments for fatigue. However, several studies recommend a combination of strategies within a neuro rehabilitation approach with a view to acting on multi fabled factors.

33:51 Afaireness should be raised about the presence, epidemology and pathophysiology of fatigue. This would promote early diagnosis and the use of appropriate treatments, preventing its negative effect in the long run. So this is the paper and you can go and look for this paper. And now, folks, please go and buy these two books because these two books bring food to the table. The Modern mocal Mentality, New Strategies to Succeed in India and the global marketplace, and the Outbreak of a Monster's Infection both were Amazon best sellers. And these days my books are not selling good. So please go and buy them and give me an honest review.

34:32 And also I want a movie or a documentary to be made out of Modern mogle Mentality and a web series or a TV serial made out of Outbreak of a Monster's Infection. And these two books are Amazon best sellers. This one was in USA and India and hot number one new release on Amazon in its category. And this one was Amazon bestseller in USA and Transfer and it was a tail flow has given me a very good evaluation. So go to my website www. Dot chanhash me dot com and give me an honest review and see what tail flix has to write. So all those movie producers please contact me at tough Chan at trrafshanhash me dot com and to tell me how do you like this these easter photographs and all. And also you know these photographs, I want to show them once again, happy and blessed Easter everyone, this one, this one, this one, and this one and this one. So these are some of the photographs, you know. And also you know, I want to tell you that please go and give me a sponsorship because if you give me sponsorship, this show is syndicated worldwide two three hundred million listeners. So please give me a sponsorship because if you give me sponsorship, this show will go on because it will go only with a sponsorship.

36:05 And please give me sponsorship, and in a very reasonable price, I will give you sponsorship. For now. You know, I am doing a special Think Life story for five thousand dollars five sittings on one hour each and then distribute it to my listeners three hundred million listeners on more than one hundred podcast outlets. And also I will give this show you know. Also I want a sponsorship where you know, two people. Like two sittings I will give you for. Two months, you know, and it will be you know, like per week I will give. I'll give you all together eight sittings you know, for two months of thirty minutes each and one will be like and an ad of five minutes. So all together you will get twenty five minutes for in conversation with me. Or you can come and promote your products and talk about it, and or you can send your employees or anybody to talk about it. And also you will get a lot of promotion.

37:17 And five thousand is a very very reasonable price. So please contact me for all this at Achan at trrafshanhash me dot com. Having said that, folks, see you next week at six pm US Eastern time and it meet and greet on talk for TV and you can go to K FOURGD dot com to see that. And also folks, I am going you know for top forty. Also, folks, you know. I have Doctor Rafshanhashmi dot Co series, you know, and that also I distribute through Talk four Media and it is also syndicated worldwide to three hundred million listeners.

38:00 So both the shows IEQ, well this one has a sounding engineer and that I do on my own. Having said that, folks, Gas and bye bye and see you next week at a meet and greet. And in the meantime we'll be doing some shows on Doctor of shanhash Me dot Co series. Gas and Bye bye. You've been listening to Meet and Great with Doctor av Shan Hashmi on K FORHD radio and Talk for TV. Tune in live right here every Thursday at six pm Eastern time. Would you love exposure to your business, product or service to over three hundred million potential listeners. Send an email to info at talkfourmedia dot com. And remember, if you miss any part of the show or want to hear it again, find our featured show on iHeartRadio or YouTube, where all past episodes are available on demand twenty four to seven. See you next Thursday at six pm Eastern time right here on K for HD and Talk for TV.