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Books, pdproducts, science, fashion and glam talk From Bollywood to Hollywood.
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It's Meet and greet with doctor Afshan Hashmi right here
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on KURHD Radio and Talk for TV. And here's your host,
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international speaker, educator, award winning entrepreneur and best selling author,
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doctor Afshan Hashmi.
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Hello everyone, this is your loving host and bestselling author,
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radio and TV personality doctor Rafshan Hashmi, live from our
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studio in Rockville, Maryland. And today, folks, I will be
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presenting a paper on hemoglobinopathies. You know, about unastable hemoglobin,
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which was part of my m ful thesis, you know.
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And this paper, you know, I chose after doing a
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search and on pebmed and before I dive into that.
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These are my two books. The first one is The
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Modern Mole mentality news strategies to succeed in India and
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the global market place. And the second one is The
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Outbreak of a Monstrous Infection. And folks, you know, I
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want a movie or a documentary to be made out
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of this book, The Modern Mole mentality news Strategies to
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succeed India and global marketplace. And just hold on, so
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now you know I want a movie or a document
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entry to be made out of this book, The Modern
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Local Mentality. And it was Amazon bestseller and hot number
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Infection is actually a best seller on USA and and
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So all those uh, all those movie and documentary producers
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please contact me at Ashan at Dr shan Hashmi dot com.
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Having said that, folks, you know, now I will go
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and talk about this paper. And the paper is homoglobin
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cast in kidney biopsies. It a logical spectrum by Jan C.
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Prema and Anila a Korean. And now, folks, I will
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go on a break and we'll come back and talk
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about this paper.
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Allow viewers around the glow. This is Doctor of Charm
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Hatchman the.
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Live for her radio show at pay four SHB and
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Talk for a TV Show. And I just wanted to
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request you that please give me a sponsorship if you
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want to want this show to continue.
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Having said that, friends, I will see you in another
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episode of K four ft radio plus Talk for TV show.
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And if you give me a sponsorship, I will give
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you a very reasonable price. And they're also you will
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get a lot of promotion as this show is syndicated.
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Your right to meet them through Christmast Years and bye bye.
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to over three hundred million potential listeners? Send an email
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now let's hear from some of our sponsors.
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Hey, monstrous infection is spreading worldwide. OMG? Is this a
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simple infection or a deliberate attempt to ruin the human population?
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Or maybe it's bio terrorism?
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What is this.
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Global infection and who is spreading it? Help us find out.
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Go to Amazon and search for the outbreak of a
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monstrous infection. The human race nature helped to make this
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go viral. Go to Amazon dot com and read the
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Outbreak of a monstrous infection to find out what happens next.
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Go now the world is depending on you and now
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doctor ash on Hashme's radio shows.
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This paper came in twenty twenty two by Journal of
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Nephrology to introduction. Intravascular hemolysis, a relatively rare condition, is
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the destruction of red blood cells the circulation resulting in
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the release of free hemoglobin. Hemoglobin is toxic to the
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tubules and causes acute kidney injury. There are a variety
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of causes for hemolysis which are very different between tropical
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and western countries. Refam bisin induced and snake environnation are
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the major causes of intravascular hemolysis in India. In western countries,
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autoimmune humolitic anemia is the major cause of humo globin
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cast nepropathy et CN. We did directrospac restro respective analysis
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of fifty six cases of ETC. And this case series
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being the target collection of ETCIAN helps in better understanding
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the clinical pathological characteristics of this rare disease. And this paper,
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you know it says financial support and sponsorship nil conflicts
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of interest. There are no conflicts of interest, so NIL,
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I don't understand how can this study be done? I
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will write to the author JC Prema and Anila A
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Korean Department of Pathology reno paths and for renal and
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neurological Pathology Genae, Tamil Nadu, India. I'm thinking like, uh
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did they do? Uh? From? Where did they do with
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their own money or with the money of uh of someone.
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Intravascular hemolysis, a relatively rare condition, is the destruction of
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red blood cells RBCs in circulation resulting in the release
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of free hemoglobin free if you if the free hemoglobin releases,
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you know, lysis occurs, and you know, hemolytic anemia and
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other conditions occur.
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My M.
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Fhil thesis were unstable hemoglobin and then we chose one
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RBC model for hemoglobin induced you know, phenyl hydrogene induced hemolyticemia.
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So that was the condition which I studied in oxidative
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stress and oxidation, in lipid oxidation as well as protein
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oxidation and how this how this affects the body. So
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that was my thesis. And here I also my thesis
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worth on effect of phenyl hydrazine on red blood cell membrane.
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And here it is that it is the destruction of
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red blood cells in circulation resulting in the release of
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free hemoglobin. Free hemoglobin are unstable hemoglobins, you know, and
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they are very very toxic to the body. Hemoglobin is
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toxic to the tabuse and causes acute kidney injury. There
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are a variety of causes for hemolysis which are very
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different between tropical and western countries. Rima, wascin induced and
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the snake where numation are the major causes of intravascular
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hemolysis in India. In western countries, autoimmune hemolytic anemia is
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the major cause of homoglobin carse nepropathy. At CN we
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did a retrospective analysis of fifty six cases of ECCY
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and this case series being the largest collection of ECCI
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and helps in better understanding the clinical pathological characteristics in
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this rare disease. So what is I will come after
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the break and we will talk about what is rema
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person induced and snake poison?
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Your agreement around the this is your house and with.
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Date and talk for few friends. I am alive Maryland
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in a country club. And I just to say that Fisk.
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Corsorship which.
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Go on.
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For money to produce these shows, having set the trends
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to sponsorship.
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Acts and why.
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So repay it is refe Pampisin also known as refampin,
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is a broad spectrum macrocyclic antibiodic antibiotic primarily used to
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treat and prevent tuber closes, neprocy and other severe microbacterial
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or bacterial infections. It works by inhibiting bacterial DNA dependent
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RNA polymerase, stopping the bacteria from replicating. So this is
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what it is, and here it says. Medical records of
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all patients were reviewed from March twenty to fifteen to
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September twenty twenty one. Biopsies showing AKI and AKI means
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acute kidney injury with pigment casts showing hemoglobin positivity were
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included in the study. There were fifty six cases of ETCAN,
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which is homoglobin cast nepropathy. So there are some nepropathies.
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You know.
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When I did my hemolytic anemia studies, heines bodies was
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formed in the effect of fenyl had rezine. Here the say,
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and which was very toxic to the human body. I
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checked it on red blood cells human red blood cells.
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And the same thing here is that the licens with
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showing hemoglobin positivity were included in the study. There were
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fifty six cases of ETCN among twenty three four hundred
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and thirty four native kidney biopsies. Clinical history and laboratory
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findings at the time of performing renal biopsy were recorded.
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For life microscope evaluation, the biopsy samples were fixed in
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ten percent buffered for formalin and formalin. You know, when
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you smell for formalin, it is so pungent a smell,
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and dead bodies are preserved in formaline, you know, And
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so that is smell is so bad. And even if
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you preserve something in formalin. That is what I have
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seen during my PhD days when I went to zoology
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department and all through my BS and all I have
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seen formalin. And here when I did clinical rotation in ARCP,
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in clinical chemistry, you know, in clinical rotations in the
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autopsy room, where I fainted. You know, That's why I
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didn't become a medical doctor. I cannot see dead bodies.
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It is too much. So I fainted there and I
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was telling my instructor that you know, I can faint here,
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and that formaline is smell is so bad that you
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know you will faint and see that. For light microscopic evaluation,
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the biopsy samples were fixed in ten percent buffered formline,
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dehydrated ingraded alcohols and embedded in paraffin. Serial two micrometer
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thick sections were cut and stayed with hemotoxelin and eosine,
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periodic acid shape jones, methani means and massive trichro mistaine.
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So these are restrains which make it immunofluorescent. The cast
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is imino fluorescent were in my PhD time. You know,
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we didn't have electron microscopy in the lab in Aliga
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Muslim urorsity, so I cannot do immino florence immonofluorescence studies.
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But here in America, you know, there are remino fluorescence studies,
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so it says study was performed in all cases during
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fluoresceine tag polychlonal rabbit anti human antibodies, so they are
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anti human anti human antibodies and they are done through immunofluorescence.
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So maybe they did Eliza. It's not clear that how
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they did it. What is the fluorescent Eliza or was
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it just looking under the microscope to I G G
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I G M I G A C three C one
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Q kappa and lambda light pains. And this was from
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Darko captain Theia California. I mean, so they did demino
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standing imino histochemistry. Maybe they did so using cell mark Rocklin.
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Antibodies for hemoglobin and myoglobin were done on the biopsies
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to confirm the diagnosis. So this is what it is. Results.
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A total of fifty six biopsies meeting the inclusion criteria
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were evaluated. The biopsy prevalence of humoglobin cars nepro pathy
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was zero point two percent. So this is a table
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here which shows that how much you know is the
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value of hemolytic anemia. So when I come back, we
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will talk about it. Hello everyone, this is Doctor of
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Sean Hashni live from a barn country club in Virginia,
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and I just wanted to say that my K four
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SHD radio and top for TV show called Me Cantry
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with Doctor of Sean Hashni is syndicated worldwide and has
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more than three hundred million listeners. And if you want
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request to please give a sponsorship because these shows require
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Of energy and money to produce.
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So I would request every month to give me sponsorship
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and your product could be promoted in a very reasonable price.
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And you can contact me Atafshan at Rushanhashmi dot com,
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Pears and bye bye.
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Would you love exposure for your business, product or service
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hear from some of our sponsors.
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A monstrous infection is spreading worldwide. Oh my god. Is
225
00:17:06.480 --> 00:17:10.640
this a simple infection or a deliberate attempt to ruin
226
00:17:10.720 --> 00:17:16.480
the human population? Or maybe it's bioterrorism. What is this
227
00:17:16.599 --> 00:17:20.359
global infection and who is spreading it? Help us find out.
228
00:17:20.519 --> 00:17:23.400
Go to Amazon and search for the Outbreak of a
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Monstrous Infection. The human race needs your help to make
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this go viral. Go to Amazon dot com and read
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the Outbreak of a Monstrous Infection to find out what
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happens next. Go now, the world is depending on you.
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00:17:48.519 --> 00:17:53.720
The Outbreak of a Monstrous Infection Chapter one, nineteen sixty
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four to twenty eighteen. And this is the sample track
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and it is read by doctor of Shan Nahi Hashmi
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00:18:01.720 --> 00:18:06.319
in a sprawling banglaw. In Potomac, Maryland, USA, lived doctor
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Honey Singh, a both certified internal medicine and family practice physician,
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along with his beautiful wife, Baby Singh. Baby Singh was
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a fashionista and was funding women's causes. Through her Honey
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Bay Foundation. She had a lady's book club by the
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name of Baby's Glam and Glitzy Club, which had many
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glam and glitzy ladies who were professionals living in Washington,
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d c. Potomac, Maryland, Virginia, and even Beverly Hills, California,